In 2004 police discover the bodies of Leslie Mazzara and Adriane Insogna of Napa, CA dead in their home, and it appeared they had died in their sleep.

A suspect who was convicted of arson and murder vehemently maintains his innocence after being sentenced to a 25-year prison term.

Live reports of the latest breaking news from around the world.

Live reports of the latest breaking news from around the world.

Live reports of the latest breaking news from around the world.

A promising young college student is found stabbed to death in her apartment and a bloody shoeprint soon points to a surprising killer hidden in plain sight.

Life in a peaceful Texas county is violently disrupted when a mysterious assailant begins to target the community's law enforcement for murder.

The scene of a brutal murder is marred by spray painted threats all over the walls and authorities discover a history of death threats that leads to the killer.

A Texas teen and her boyfriend are savagely attacked on Valentine's Day, causing her death while boyfriend escapes - a case that goes cold for 50 years.

After three Indiana construction workers are found dead on their work site, detectives find only one clue - the shoeprint of one of the killers.

A newly released Texas man claims he will change his life, only to become caught up in a murder case; back in prison, he turns to forensics.

A Californian businesswoman who frequently battled illness succumbs, but her doctors are unable to determine a plausible explanation for her death.

When the body of a young criminology student is discovered wrapped in a blanket along an abandoned road in Brooklyn, the authorities suspect an unusual culprit.

A 79-year-old woman is found murdered in her home, and investigators suspect her husband is to blame until shell casings reveal a shocking killer.

After a young single mother is abducted and found stabbed to death, detectives use shoe impressions to narrow down their list of suspects.

A 23-year-old Marine dies in his bedroom, which doctors believe to be a heart attack - but after arsenic is found inside him, his wife is charged with murder.

After an 18-year-old girl is kidnapped while talking on a pay phone, forensic evidence on her clothes point police to a suspect who says he didn't act alone.

Investigators seek a pair of killers who burned a murder victim and stabbed them 24 times, with two different knives.

Three victims of an Indiana serial rapist identify the same man, but forensic evidence indicates that another man is the real culprit.

A couple's murder is thought to be drug related, but there was no evidence to link the suspects, until the victims' dog pitched in.

Doctor's fiancée falls ill, and it is up to forensic scientists and a hidden camera to discover the cause.

Faryion Wardrip held a startling secret behind his life as a Sunday school teacher, though was able to go unnoticed for years until a paper cup gave him away.

Police find a discarded car on a Philadelphia highway and soon discover that its driver is the victim of murder and her body is covered with strange marks.

A South Dakota minister finds his wife dead in the bathtub and investigators initially believe she committed suicide until new information points to murder.

A woman vanishes after stopping her car on a busy highway, and the trail turns so cold that new forensic techniques are required.

After Tracy Jo Shine disappeared, her new affiliation with the some members of the Aryan Brotherhood comes into the investigation as suspect.

A 60-year-old man seems to be dying and he believes his business partner might be the one poisoning him, so he takes those suspicions to the police.

Girl's father is the prime suspect when she goes missing and he confesses to killing her however his confession has more to do with mental illness than guilt.

Woman is murdered after she leaves an Alaska bar and investigators must use extraordinary techniques in order to obtain evidence from the body.

Emelita Villa came to Texas from the Philippines as a shy, impoverished, mail-order bride. Six and a half years later, she disappeared.

A pawn shop owner uncovers a distinctive pendant necklace that turns out to be a key piece of evidence concerning a 2-year-old double homicide case.

When emergency personnel are called to attend to an apparent heart attack victim, no one suspects foul play until police look into his girlfriend.

After police investigate a series of burglaries they find evidence from the scene of the unsolved murder of a young girl killed in her own home.